This is the question every single customer is asking: "How Much Resveratrol Supplements Should You Take?" Numbers are all over. However, since the research of this topic is still considered to be on its infancy, a well-established dosage is yet to be defined.
In a lab test, mice fed with resveratrol supplements for fifteen weeks had better treadmill endurance than the other population not given the substance. The researchers say that the dose provided was 400mg/kg of body weight. If it was a human weighing about 80kg, the dosage used for the mice would come to 32,000mg/day. But since fact dictates that humans have slower metabolic rates compared to mice, it would change to around 4,571mg/day, still a very large number and not proved safe by any research to human subjects.
As of today, the correct dosage is still a huge issue. But, some have already made a classification of the dosage being: Low, Moderate and High Dosages. The Low Dosage would range from 100 mg - 500 mg/day. Moderate Dosage, however, starts from 500 mg - 1,500 mg/day. Anything taken above 1,500 mg/day is considered High Dosage.
This however, isn't followed by everyone. The human equivalent of a 20 mg/day of resveratrol created pronounced anti-aging gene-expression changes in lab mice and a pharmaceutical company actually encourages customers to take resveratrol in that dosage. Another company claims that 15 mg taken two times a day with a 9-10 hour interval is necessary to get the best benefit. However, this is for the weight loss property of the supplementation since the purpose of taking two separate dosages of 15mg is to keep the Sirtuin 1 gene activated which helps in burning fat and converting them into functional energy.
Another firm asserts that large doses of their supplementation, which they called "mega doses," are necessary to obtain best effects. They can go from 500mg to 1000 mg per dose, equivalent to Moderate Dosage, as previously mentioned.
A volunteer study was made using these mega doses and side effects were actually seen with the people taking such high doses. Those unwanted side effects, all reversible, include anemia, diarrhea, anxiety and over-thinning of the blood.
In choosing the dosage you think is appropriate for you, it is crucial to know the amount of additives in the resveratrol supplement at hand. If additives are present, a low dosage could be a good idea to save your self from nasty negative effects. Naturally, this forbids you from getting maximum benefits from the compound so it is advisable to purchase only pure resveratrol-to give you the greatest possible benefits and simultaneously, keep you from unwanted effects.
The bioavailability of the supplementation is also a factor to be considered. This is the amount available for the body to be consumed after it has undergone the passes necessary for it to be absorbed. New formulations of the supplementation are enabling smaller doses to yield a higher bioavailability than ever before.
To be safe, some suggest a ramp-up period to the highest dose. This means you begin with a low dose and continue with it for a week or two until you are convinced that there are no reactions to the supplement. Once done with the first 2 weeks or so, you can now increase the dosage around 20% and stick with that for another couple of weeks, and so on and so forth. Rest assured that resveratrol doesn't create major problems. It's listed by the EPA as a non-toxic substance backed with numerous human trials.
As for the question "How Much Resveratrol Supplements Should You Take?" the answer is, uncertain.
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